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IVF is performed in cases of infertility which may be due to
Advanced age of the woman
Damaged or blocked Fallopian tubes
Decreased sperm count and blockage causing male infertility
Unexplained infertility
Endometriosis
Ovulation disorders ,uterine fibroids
I: Stimulation of ovaries also called super ovulation
Medicines, called fertility drugs, are given to the woman to boost egg production.
Blood tests for hormone levels and ultrasounds to examine ovaries are performed regularly .
II: Egg retrieval/ follicular aspiration
Procedure called follicular aspiration, is done to remove the eggs from the woman's body.
The is performed as an outpatient procedure under sedation with no incision only by using ultrasound images as guide, a thin needle is inserted into the ovary and sacs (follicles) containing the eggs. The needle is connected to a suction device, which pulls the eggs and fluid out of each follicle, one at a time.
The procedure is repeated for the other ovary.
In few cases laparoscopy may be performed to remove the eggs .
If a woman does not or cannot produce any eggs, donor eggs may be used.
III: Insemination
Sperm is placed together with the best quality eggs. The mixing of the sperm and egg is called insemination.
Eggs and sperm are then stored in an environmentally controlled chamber. The sperm most often enters (fertilizes) an egg a few hours after insemination.
In few cases the sperm may be directly injected into the egg. This is called intracytoplasmic sperm injection (ICSI).
Many a doctors routinely do ICSI on some of the eggs, even if things appear normal.
IV : Transfer of embryo to uterus
When the fertilized egg divides, it becomes an embryo. Laboratory staff will regularly check the embryo to make sure it is growing properly. Within about 5 days, a normal embryo has several cells that are actively dividing
Embryos are placed into the uterus 3 to 5 days after fertilization through a catheter
If an embryo implants in the lining of the womb and grows, pregnancy results.
More than one embryo may be placed into the uterus at the same time, which can lead to twins, triplets, or more.
Rest adviced for the remainder day , most can return to normal activities by next day .
Complete bed rest not required .
Recommended daily hormone progesterone for 8-10 weeks for normal course of pregnancy and to avoid miscarriage.
Pregnancy test performed about 12 to 14 days after the embryo transfer.
Chances of multiple pregnancies as more than one embryo is placed in uterus ,leading high risk of premature birth and low birth weight baby.
Egg retrieval can result in bleeding, infection, and damage to ovaries and surrounding structures.
There may be temporary cramping after egg retrieval which may last for a day or two.
Many couples suffer psychological stress and depression especially if IVF not successful .
Financially and emotionally challenging treatment .
Rarely fertility medications may cause ovarian hyperstimulation syndrome (OHSS).
The cost to the patient depends on a variety of factors like
The hospital, the patient chooses.
Fee for the team of doctors.
Medicines.
Standard test and diagnostic procedures.
Cost of the procedure